| id |
35a4984d-1837-4c1b-b52c-72ec3f143703 |
| user_id |
8684964a-bab1-4235-93a8-5fd5e24a1d0a |
| job_id |
vkpghfkj-5237 |
| base_model_name |
xevyo |
| base_model_path |
/home/sid/tuning/finetune/backend/output/xevyo-bas /home/sid/tuning/finetune/backend/output/xevyo-base-v1/merged_fp16_hf... |
| model_name |
Telomere shortening rate |
| model_desc |
Telomere shortening rate predicts species life spa |
| model_path |
/home/sid/tuning/finetune/backend/output/vkpghfkj- /home/sid/tuning/finetune/backend/output/vkpghfkj-5237/merged_fp16_hf... |
| source_model_name |
xevyo |
| source_model_path |
/home/sid/tuning/finetune/backend/output/xevyo-bas /home/sid/tuning/finetune/backend/output/xevyo-base-v1/merged_fp16_hf... |
| source_job_id |
xevyo-base-v1 |
| dataset_desc |
This scientific paper presents strong evidence tha This scientific paper presents strong evidence that the rate at which telomeres shorten—not the length of telomeres at birth—is the key biological factor that predicts how long a species lives. Telomeres, the protective caps on chromosome ends, naturally shorten as organisms age. When they shorten too much, cells stop dividing and enter senescence, contributing to aging.
Researchers measured telomere length in multiple species—including mice, goats, dolphins, flamingos, vultures, gulls, reindeer, and elephants—using a standardized high-precision technique (HT Q-FISH). They discovered the following:
⭐ Key Findings
1. Initial telomere length does NOT predict lifespan
Some short-lived species (like mice) have extremely long telomeres at birth, while long-lived species (like humans) start with relatively short telomeres.
➡️ There is no meaningful correlation between starting telomere length and species longevity.
⭐ 2. Telomere shortening rate strongly predicts lifespan
Species that live longer lose telomere length much more slowly each year.
Humans lose ~70 base pairs/year
Mice lose ~7,000 base pairs/year
Across all species tested, a slower telomere shortening rate strongly matched longer maximum and average lifespans, with very high statistical accuracy (R² up to 0.93).
➡️ The faster telomeres shorten, the shorter the species’ life.
➡️ The slower they shorten, the longer the species can live.
This makes telomere shortening rate one of the most powerful biological predictors of lifespan ever measured.
⭐ 3. Other factors (body mass & heart rate) correlate with longevity—but not as strongly
Larger species generally live longer and have slower telomere shortening.
Higher heart rates correlate with faster telomere shortening.
However, telomere shortening rate remains the strongest predictor even when all factors are combined.
⭐ Core Conclusion
The study concludes that cellular aging driven by telomere shortening is a universal mechanism across mammals and birds. Once telomeres reach a critically short point, cells accumulate DNA damage, senescence rises, and organismal aging accelerates.
➡️ Therefore, telomere shortening rate can accurately predict a species’ lifespan.
➡️ This makes telomere biology a central mechanism for understanding aging across the animal kingdom.... |
| dataset_meta |
{"num_examples": 148, "bad_lines": {"num_examples": 148, "bad_lines": 0}... |
| dataset_path |
/home/sid/tuning/finetune/backend/output/vkpghfkj- /home/sid/tuning/finetune/backend/output/vkpghfkj-5237/data/vkpghfkj-5237.json... |
| training_output |
null |
| status |
completed |
| created_at |
1764447596 |
| updated_at |
1764449035 |
| source_adapter_path |
NULL |
| adapter_path |
/home/sid/tuning/finetune/backend/output/vkpghfkj- /home/sid/tuning/finetune/backend/output/vkpghfkj-5237/adapter... |
| plugged_in |
False |